Research

TB-500 (Thymosin β4 Fragment): Actin Sequestration, Cell Migration, and Angiogenic Signaling

Preclinical review of TB-500 (Thymosin β4 Ac-SDKP fragment): G-actin sequestration mechanism via the LKKTET domain, ILK/PINCH/parvin signaling, VEGF and integrin β1 upregulation, and data from cell migration, wound healing, and angiogenesis models in rodents.